@article{Candela_Marra_Tutolo_Rodríguez-Sánchez_Macek_Cathelineau_Montorsi_Salonia_Sanchez Salas_2022, title={Postoperative Non-Surgical Interventions to Improve Urinary Continence After Robot-Assisted Radical Prostatectomy: A Systematic Review}, volume={3}, url={https://siuj.org/index.php/siuj/article/view/175}, DOI={10.48083/DPRH8648}, abstractNote={<p>Background: The occurrence of postoperative urinary incontinence (UI) remains a problem for patients undergoing<br>robot-assisted radical prostatectomy (RARP). Non-surgical interventions (NSI) in addition to intraoperative<br>techniques and patient behavioral changes have been proposed to improve urinary continence (UC) recovery after<br>RARP. However, to date, the real clinical impact of postoperative NSI remains not well characterized.<br>Materials and Methods: We performed a Systematic Review in April 2021, using Allied and Complementary<br>Medicine (AMED), Embase, and MEDLINE according to the PRISMA recommendations and using the Population,<br>Intervention, Comparator and Outcome (PICO) criteria. Primary outcome of interest was the impact of NSI on UC<br>recovery rate and time to achieve UC after RARP. Secondary outcomes of interest were the assessment of patient<br>adherence to NSI, risk factors associated with UI, and correlation between postoperative NSI and sexual activity<br>recovery.<br>Results: A total of 2758 articles were screened, and 8 full texts including 1146 patients were identified (3 randomized<br>controlled trials, 3 prospective single-arm trials, and 2 retrospective series). Postoperative NSI of interest included<br>pelvic floor muscle training (PFMT) (n = 6 studies) and administration of oral medications (solifenacin) (n = 2<br>studies). PFMT appeared to increase UC rates and to accelerate time to achieve UC in the early postoperative period.<br>Similarly, solifenacin provided higher rates of UC recovery and contributed to a certain degree of symptomatic relief.<br>There was a great variability regarding NSI features and data reporting among studies. Major limitations were the<br>small sample sizes and the short follow-up.<br>Conclusion: Postoperative NSI to manage UI after RARP include PFMT and solifenacin administration. Both seem<br>to modestly improve early UC recovery. Nonetheless, evidence supporting their routinely use is still weak and lacks<br>appropriate follow-up to evaluate possible benefits on long-term UC recovery.</p&gt;}, number={2}, journal={Société Internationale d’Urologie Journal}, author={Candela, Luigi and Marra, Giancarlo and Tutolo, Manuela and Rodríguez-Sánchez, Lara and Macek, Petr and Cathelineau, Xavier and Montorsi, Francesco and Salonia, Andrea and Sanchez Salas, Rafael}, year={2022}, month={Mar.}, pages={88–100} }